FLX 787

Drug Profile

FLX 787

Alternative Names: FLX-787-ODT; FLX787; TRP activators - Flex Pharma; TRPA1 activators - Flex Pharma; TRPV1 activators - Flex Pharma

Latest Information Update: 10 Nov 2017

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At a glance

  • Originator Flex Pharma
  • Class Small molecules
  • Mechanism of Action TRPA1 protein stimulants; TRPV cation channel agonists; TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Charcot-Marie-Tooth disease; Multiple sclerosis
  • Phase I Motor neuron disease
  • Preclinical Neuromuscular disorders

Most Recent Events

  • 07 Nov 2017 Flex Pharma plans a phase I/II trial in Amyotrophic lateral sclerosis in the US (NCT03334786)
  • 06 Nov 2017 Efficacy and safety data from a phase II trial in Amyotrophic lateral sclerosis released by Flex Pharma
  • 16 Oct 2017 Phase-II clinical trials in Charcot-Marie-Tooth disease in USA (PO)
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