Research programme: toll-like receptor antagonist - Janus Biotherapeutics/Roche

Drug Profile

Research programme: toll-like receptor antagonist - Janus Biotherapeutics/Roche

Alternative Names: JB6121; TLR inhibitor - Janus Biotherapeutics/Roche; Toll-like receptor inhibitor - Janus Biotherapeutics/Roche

Latest Information Update: 05 Jan 2016

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At a glance

  • Originator Janus Biotherapeutics
  • Developer Janus Biotherapeutics; Roche
  • Class Small molecules
  • Mechanism of Action Toll-like receptor 7 antagonists; Toll-like receptor 8 antagonists; Toll-like receptor 9 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Systemic lupus erythematosus

Most Recent Events

  • 20 Aug 2015 Janus Biotherapeutics and Roche agree to co-develop TLR Antagonist in USA for Autoimmune Disorders
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