Astarabine

Drug Profile

Astarabine

Alternative Names: Ara-C asparagine conjugate; Asparagine ara-C conjugate; Asparagine cytarabine conjugate; Astarabine; BSR-236; Cytarabine asparagine conjugate

Latest Information Update: 03 Oct 2017

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At a glance

  • Originator BioSight
  • Class Amino acids; Antineoplastics; Arabinonucleosides; Drug conjugates; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Acute lymphoblastic leukaemia; Acute myeloid leukaemia
  • Preclinical Chronic myeloid leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 20 Sep 2017 BioSight completes a phase I/II trial for Acute myeloid leukaemia and Acute lymphoblastic leukaemia in Israel (NCT02544438)
  • 09 Aug 2017 BioSight completes enrolment in its phase I/II trial for Acute myeloid leukaemia and Acute lymphoblastic leukaemia in Israel
  • 02 Jun 2017 Updated efficacy and safety data from a phase I/II trial in Acute myeloid leukaemia and Acute lymphocytic leukaemia presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
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