Drug Profile


Alternative Names: Ara-C asparagine conjugate; Asparagine ara-C conjugate; Asparagine cytarabine conjugate; Astarabine; BSR-236; Cytarabine asparagine conjugate

Latest Information Update: 18 Feb 2017

Price : $50

At a glance

  • Originator BioSight
  • Class Amino acids; Antineoplastics; Arabinonucleosides; Drug conjugates; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Acute lymphoblastic leukaemia; Acute myeloid leukaemia
  • Preclinical Chronic myeloid leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 03 Dec 2016 Interim adverse events and efficacy data from a phase I/II trial in Acute myeloid leukaemia and Acute lymphocytic leukaemia presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-2016)
  • 17 May 2016 BioSight plans a phase IIb study in Acute myeloid leukaemia in USA Europe and Israel
  • 19 Apr 2016 BioSight completes enrolment in its phase I/II trial for Acute myeloid leukemia and Acute lymphoblastic leukemia in Israel
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