RG 7386

Drug Profile

RG 7386

Alternative Names: FAP-DR5 - Roche; RG7386; RO-6874813

Latest Information Update: 02 Nov 2017

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At a glance

  • Originator Roche
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action Cell death stimulants; Immunomodulators; TRAIL receptor 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 30 Oct 2017 Efficacy and adverse event data from a phase I trial in Solid tumours presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2017 (AACR-NCI-EORTC-2017)
  • 25 Sep 2015 Preclinical trials in Solid tumours in USA (IV)
  • 25 Sep 2015 Roche plans a phase I trail for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in USA (NCT02558140)
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