Drug Profile


Alternative Names: NEO-PV-01; Neoantigen-based vaccine - Neon Therapeutics; NeoAntigen-peptides; NeoVax; Personalized-neoantigen-cancer-vaccine-Neon-Therapeutics

Latest Information Update: 11 Nov 2016

Price : $50

At a glance

  • Originator Broad Institute; Dana-Farber Cancer Institute
  • Developer Bristol-Myers Squibb; Dana-Farber Cancer Institute; Neon Therapeutics
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Bladder cancer; Glioblastoma; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 06 Jul 2017 Dana-Farber Cancer Institute, in collaboration with Neon Therapeutics and Oncovir, plans a phase I trial for Chronic lymphocytic leukaemia (First-line therapy) in USA (NCT03219450)
  • 11 Nov 2016 Dana-Farber Cancer Institute plans a phase I trial for Renal cell carcinoma (Late-stage disease, Metastatic disease, Combination therapy) in USA (NCT02950766)
  • 01 Oct 2016 Phase-I clinical trials in Bladder cancer (Inoperable/Unresectable, Metastatic disease, Late-stage disease, Second-line therapy or greater, Combination therapy) in USA (Parenteral) (NCT02897765)
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