Drug Profile


Alternative Names: NEO-PV-01; Neoantigen-based vaccine - Neon Therapeutics; NeoAntigen-peptides; NeoVax; Personalized-neoantigen-cancer-vaccine-Neon-Therapeutics

Latest Information Update: 27 Jul 2017

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At a glance

  • Originator Broad Institute; Dana-Farber Cancer Institute
  • Developer Bristol-Myers Squibb; Dana-Farber Cancer Institute; Neon Therapeutics
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Bladder cancer; Glioblastoma; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 25 Jul 2017 Apexigen and Neon Therapeutics enter into a clinical trial collaboration for a phase Ib trial in Malignant melanoma
  • 25 Jul 2017 Apexigen and Neon Therapeutics plan a phase Ib trial in Malignant melanoma (Combination therapy)
  • 06 Jul 2017 Dana-Farber Cancer Institute, in collaboration with Neon Therapeutics and Oncovir, plans a phase I trial for Chronic lymphocytic leukaemia (First-line therapy) in USA (NCT03219450)
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