Research programme: chitinase inhibitors - OncoArendi Therapeutics

Drug Profile

Research programme: chitinase inhibitors - OncoArendi Therapeutics

Alternative Names: AMCase inhibitors – OncoArendi Therapeutics; Chitotriosidase inhibitors - OncoArendi Therapeutics; OAT 889; OATD 01

Latest Information Update: 17 Nov 2017

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At a glance

  • Originator Yale University
  • Developer OncoArendi Therapeutics
  • Class Antiasthmatics; Nonsteroidal anti-inflammatories; Small molecules
  • Mechanism of Action Acidic mammalian chitinase inhibitors; Chitinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Asthma; Chronic obstructive pulmonary disease

Most Recent Events

  • 09 Oct 2017 OncoArendi Therapeutics receives approval from German Federal Institute for Drugs and Medical Devices (BfArM) for initiation of a phase I trial of OATD 01 in Asthma (In volunteers)
  • 09 Oct 2017 OncoArendi Therapeutics plans a multiple-ascending dose clinical trial of OATD-01 in 2018
  • 09 Sep 2017 Preclinical trials in Chronic obstructive pulmonary disease in Poland (PO) before September 2017
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