Drug Profile


Alternative Names: anti-MAGE A3/A6 TCR

Latest Information Update: 21 Mar 2016

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At a glance

  • Originator National Cancer Institute (USA)
  • Class Cell therapies
  • Mechanism of Action Gene transference; MAGEA-3-protein-modulators; T lymphocyte replacements; T-cell receptor antigen modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 21 Mar 2016 Phase-II clinical trials for Solid tumours in USA (Kite Pharma pipeline; March 2016)
  • 29 Feb 2016 Kite Pharma plans to file an IND application with the US FDA for a TCR product candidate that targets a MAGE antigen expressed on Solid tumours (Kite Pharma 8-K; February 2016)
  • 21 Oct 2015 Kite Pharma in-licenses T cell receptor-based products directed against MAGE A3/A6 in Solid tumours expressing MAGE from National Institute of Cancer
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