Drug Profile


Alternative Names: Anti-CEA CAR-T; Anti-CEA T-cells; CAR-T CEA; CAR-T-CEA-therapy; CEA CART; Designer T-cells

Latest Information Update: 12 Apr 2017

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At a glance

  • Originator BDL Products, Inc.; CARgenix Holdings LLC
  • Developer Roger Williams Medical Center
  • Class Antineoplastics; CAR-T cell therapies
  • Mechanism of Action Carcinoembryonic antigen inhibitors; Cytotoxic T lymphocyte stimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Liver metastases

Most Recent Events

  • 03 Apr 2017 Safety and efficacy results from the phase I HITM-SIR clinical trial in Liver metastases released by Sorrento Therapeutics
  • 03 Apr 2017 TNK Therapeutics in collaboration with Roger Williams Cancer Center plans a phase II trial for Liver metastases in USA
  • 01 Feb 2017 The Roger Williams Medical Center in collaboration with the University of Colorado initiates the phase-I HITM-SURE clinical trial in Liver metastases (Second-line or greater therapy, Inoperable/Unresectable) in USA (Intrahepatic) (NCT02850536)
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