BFKB 8488A

Drug Profile

BFKB 8488A

Alternative Names: BFKB8488A; RG 7992; RO 7040551

Latest Information Update: 04 Oct 2017

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At a glance

  • Originator Genentech
  • Class Antihyperglycaemics; Bispecific antibodies; Insulin sensitisers
  • Mechanism of Action KLB protein inhibitors; Type 1 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Type 2 diabetes mellitus

Most Recent Events

  • 11 Sep 2017 Pharmacokinetic and efficacy data from a phase I trial in Type 2 diabetes mellitus presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD-2017)
  • 09 Jun 2017 Interim efficacy and adverse events data from a phase I trial in Type-2 diabetes mellitus presented at the 77th Annual Scientific Sessions of the American Diabetes Association (ADA-2017)
  • 28 Mar 2017 Genentech completes a phase I trial in Type-2 diabetes mellitus (In volunteers) in USA (NCT02593331)
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