BLU 285

Drug Profile

BLU 285

Alternative Names: BLU-285

Latest Information Update: 14 Jun 2017

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At a glance

  • Originator Blueprint Medicines
  • Class Antineoplastics; Skin disorder therapies; Small molecules
  • Mechanism of Action Platelet derived growth factor alpha receptor antagonists; Proto oncogene protein c-kit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Systemic mastocytosis; Gastrointestinal stromal tumours
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Gastrointestinal stromal tumours; Solid tumours; Systemic mastocytosis

Most Recent Events

  • 05 Jun 2017 BLU 285 receives Breakthrough Therapy status for Gastrointestinal stromal tumours (Inoperable/Unresectable, Metastatic disease) in USA
  • 05 Jun 2017 Blueprint Medicines announces intention to submit NDA to the US FDA for Gastrointestinal stomal tumours
  • 05 Jun 2017 Efficacy, safety and pharmacokinetics data from a phase I trial in Gastrointestinal stomal tumours presented at the annual meeting of American Society of Clinical Oncology (ASCO-2017)
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