MAGE A10-specific T-cells - Adaptimmune

Drug Profile

MAGE A10-specific T-cells - Adaptimmune

Alternative Names: MAGE A-10 TCR; MAGE A10-transduced lymphocytes; MAGE-A10 SPEAR T-cell therapy

Latest Information Update: 11 Apr 2017

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At a glance

  • Originator Adaptimmune
  • Developer Adaptimmune; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Gene therapies; T lymphocyte cell therapies
  • Mechanism of Action Cell replacements; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Non-small cell lung cancer
  • Phase I Bladder cancer; Head and neck cancer; Malignant melanoma; Urogenital cancer
  • Preclinical Solid tumours

Most Recent Events

  • 13 Mar 2017 Adaptimmune Therapeutics has patents pending for MAGE A10-specific T-cells in USA and United Kingdom
  • 18 Oct 2016 Phase-I clinical trials in Malignant melanoma, Head and neck cancer and Urogenital cancer (Inoperable/Unresectable, Metastatic disease) in USA (unspecified route)
  • 01 Oct 2016 Phase-I clinical trials in Bladder cancer in USA (unspecified route) (NCT02989064)
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