RA 101495

Drug Profile

RA 101495

Alternative Names: RA101495

Latest Information Update: 01 Aug 2017

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At a glance

  • Originator Ra Pharmaceuticals
  • Class Cyclic peptides; Macrocyclic compounds
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Paroxysmal nocturnal haemoglobinuria
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Paroxysmal nocturnal haemoglobinuria
  • Preclinical Lupus nephritis; Myasthenia gravis

Most Recent Events

  • 31 Jul 2017 RA 101495 receives Orphan Drug status for Paroxysmal nocturnal haemoglobinuria in USA
  • 27 Jun 2017 Initial safety and efficacy data from a phase II trial in Paroxysmal nocturnal haemoglobinuria released by Ra Pharmaceuticals
  • 17 Mar 2017 Phase-II clinical trials in Paroxysmal nocturnal haemoglobinuria in Hungary (SC) (EudraCT2016-003523-34)
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