RA 101495

Drug Profile

RA 101495

Alternative Names: RA101495

Latest Information Update: 12 Jan 2018

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At a glance

  • Originator Ra Pharmaceuticals
  • Class Cyclic peptides; Macrocyclic compounds
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Paroxysmal nocturnal haemoglobinuria
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Myasthenia gravis; Paroxysmal nocturnal haemoglobinuria
  • Preclinical Lupus nephritis

Most Recent Events

  • 08 Jan 2018 Ra Pharmaceuticals initiates enrolment in a phase Ib pharmacokinetic trial for Lupus nephritis and Paroxysmal-nocturnal-haemoglobinuria
  • 04 Dec 2017 Ra Pharmaceuticals announces intention to engage with regulators for advancing RA 101495 into a registrational programme in Paroxysmal nocturnal haemoglobinuria
  • 04 Dec 2017 Interim efficacy and adverse events data from a phase II trial in Paroxysmal nocturnal haemoglobinuria released by Ra Pharmaceuticals
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