MB 102

Drug Profile

MB 102

Alternative Names: Anti-CD123 chimeric antigen receptor T cell therapy - Mustang Bio; MB 102 - Mustang Bio; MB102

Latest Information Update: 12 Dec 2017

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At a glance

  • Originator City of Hope National Medical Center
  • Developer Mustang Bio
  • Class Antineoplastics; CAR-T cell therapies; Cell therapies; Gene therapies
  • Mechanism of Action Cytotoxic T lymphocyte stimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Acute myeloid leukaemia

Most Recent Events

  • 08 Dec 2017 Efficacy and adverse events data from a phase I trial in Acute myeloid leukaemia presented at 59th Annual Meeting and Exposition of the American Society of Hematology (ASH-Hem- 2017)
  • 01 Oct 2017 UMass Medicine Science Park and Mustang bio entered into an agreement to support the clinical development and commercialisation of CAR T therapies
  • 01 Feb 2017 Mustang Bio entered into three amended and restated exclusive patent license agreements for MB 102
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