DTX 101

Drug Profile

DTX 101

Alternative Names: AAVrh10FIX; DTX101; Wild-type FIX AAVrh10 vector

Latest Information Update: 08 Nov 2017

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At a glance

  • Originator Dimension Therapeutics
  • Class Antihaemorrhagics; Gene therapies
  • Mechanism of Action Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemophilia B
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Haemophilia B

Most Recent Events

  • 07 Nov 2017 Dimension Therapeutics has been acquired by Ultragenyx Pharmaceutical
  • 10 May 2017 Dimension Therapeutics terminates a phase I/II trial in Haemophilia B in USA and Bulgaria as the analysis did not meet the company's minimum target product profile for continued development or future commercialisation (Parenteral) (NCT02618915)
  • 10 May 2017 Discontinued - Phase-I/II for Haemophilia B in USA and Bulgaria (Parenteral)
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