Anti-CD19 chimeric antigen receptor T cell therapy - Intrexon/ZIOPHARM

Drug Profile

Anti-CD19 chimeric antigen receptor T cell therapy - Intrexon/ZIOPHARM

Latest Information Update: 27 Feb 2017

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At a glance

  • Originator Intrexon Corporation; ZIOPHARM Oncology
  • Developer Intrexon Corporation; National Cancer Institute (USA); University of Texas M. D. Anderson Cancer Center; ZIOPHARM Oncology
  • Class Antineoplastics; CAR-T cell therapies
  • Mechanism of Action Apoptosis stimulants; Gene expression modulators; Gene transference; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I B cell lymphoma; Leukaemia
  • Preclinical Multiple myeloma

Most Recent Events

  • 31 Jan 2017 Pharmacodynamics data from a preclinical study in Cancer released by ZIOPHARM Oncology
  • 31 Jan 2017 ZIOPHARM Oncology plans a phase I trial of third-generation anti-CD19 CAR T-cell therapy for Cancer in 2017
  • 03 Dec 2016 Preclinical trials in Multiple myeloma in USA before December 2016
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