AGEN 1884

Drug Profile

AGEN 1884

Alternative Names: AGEN-1884

Latest Information Update: 31 Aug 2017

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At a glance

  • Originator 4-Antibody; Ludwig Institute for Cancer Research
  • Developer Agenus; Recepta biopharma
  • Class Antineoplastics; Immunoglobulins; Monoclonal antibodies
  • Mechanism of Action Cytotoxic T-lymphocyte antigen 4 inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I Cancer

Most Recent Events

  • 15 Aug 2017 Phase-II clinical trials in Non-small cell lung cancer (First-line therapy, Combination therapy, Metastatic disease) in Australia, New Zealand (IV) (ACTRN12617001061325)
  • 24 Jul 2017 Agenus plans a phase IIa trial of AGEN 1884 in combination with pembrolizumab for Non Small Cell Lung Cancer (First line therapy, Combination therapy, Metastatic disease) in Australia and New Zealand in August 2017 (ACTRN12617001061325p)
  • 05 Jun 2017 Interim efficacy and adverse events data from a phase I dose escalation trial in Cancer released by Agenus
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