Glecaprevir/pibrentasvir - Abbvie

Drug Profile

Glecaprevir/pibrentasvir - Abbvie

Alternative Names: 2DAA; ABT-493/ABT-530; GLE/PIB; HCV Next Gen; MAVIRET; MAVYRET; Pibrentasvir/glecaprevir

Latest Information Update: 16 Oct 2017

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At a glance

  • Originator AbbVie; Enanta Pharmaceuticals
  • Developer AbbVie
  • Class Antivirals; Aza compounds; Benzimidazoles; Carbamates; Cyclic ethers; Cyclopentanes; Cyclopropanes; Fluorobenzenes; Piperidines; Pyrrolidines; Quinoxalines; Small molecules
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors; Hepatitis C virus NS3 protein inhibitors; Hepatitis C virus NS4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Hepatitis C

Most Recent Events

  • 29 Sep 2017 Phase III clinical trials in Hepatitis C (Treatment-naïve, Treatment-experienced) in China (NCT03235349)
  • 27 Sep 2017 Registered for Hepatitis C (Treatment-naive, Treatment-experienced) in Japan (PO)
  • 21 Aug 2017 Kirby Institute initiates the phase IIIb SMART-C trial for Hepatitis C (Treatment naive) in Australia (NCT03117569)
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