TK 216

Drug Profile

TK 216

Alternative Names: TK-216

Latest Information Update: 12 May 2017

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At a glance

  • Originator Tokalas, Inc.
  • Developer Oncternal Therapeutics, Inc.
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-fli-1 inhibitors; Proto-oncogene-protein-c-ets inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ewing's sarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Ewing's sarcoma
  • Preclinical Acute myeloid leukaemia; Diffuse large B cell lymphoma; Glioblastoma; Prostate cancer

Most Recent Events

  • 01 Apr 2017 Pharmacodynamics data from preclinical studies in Ewing's sarcoma presented at the 108th Annual Meeting of the American Association of Cancer Research (AACR-2017)
  • 27 Jan 2017 Preclinical trials in Glioblastoma in USA (unspecified route)
  • 27 Jan 2017 Preclinical trials in Prostate cancer in USA (unspecified route)
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