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PLX 51107

Drug Profile

PLX 51107

Alternative Names: PLX-51107

Latest Information Update: 26 Feb 2024

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At a glance

  • Originator Plexxikon
  • Developer Plexxikon; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Oxazoles; Pyrazoles; Pyridines; Small molecules
  • Mechanism of Action BRD1 protein inhibitors; BRD2 protein inhibitors; BRD3 protein inhibitors; BRD4 protein inhibitors; Proto oncogene protein c-myc inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Graft-versus-host disease; Myelodysplastic syndromes; Solid tumours

Most Recent Events

  • 28 Sep 2023 Plexxikon completes a phase I/II clinical trials in Graft-versus-host disease (Second-line therapy or greater) in USA (PO) (NCT04910152)
  • 07 Jul 2022 Discontinued - Phase-I for Acute myeloid leukaemia (Combination therapy, Second-line therapy or greater) in USA (PO)
  • 07 Jul 2022 Discontinued - Phase-I for Acute myeloid leukaemia (Late-stage disease, Second-line therapy or greater) in USA (unspecified route)
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