Ambrisentan/tadalafil - GlaxoSmithKline

Drug Profile

Ambrisentan/tadalafil - GlaxoSmithKline

Alternative Names: Tadalafil/ambrisentan

Latest Information Update: 17 Aug 2017

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At a glance

  • Originator GlaxoSmithKline
  • Developer GlaxoSmithKline; Hammersmith Medicines Research
  • Class Antihypertensives; Benzodioxoles; Carbolines; Indoles; Phenylpropionates; Pyridazines; Small molecules
  • Mechanism of Action Endothelin A receptor antagonists; Type 5 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Pulmonary hypertension

Most Recent Events

  • 04 Aug 2017 GlaxoSmithKline completes a phase I trial in Pulmonary hypertension (In volunteers) in United Kingdom (PO) (NCT02688387)
  • 01 Mar 2016 Phase-I clinical trials in Pulmonary hypertension (In volunteers) in United Kingdom (PO) (NCT02688387)
  • 18 Feb 2016 GlaxoSmithKline plans a phase I pharmacokinetics trial in Healthy volunteers in United Kingdom (PO) (NCT02688387)
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