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DEN 181

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Drug Profile

DEN 181

Alternative Names: CEN-181; Curcusome-RA; CurcusomeTM-RA; DEN-181

Latest Information Update: 05 Jan 2022

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At a glance

  • Originator University of Queensland
  • Developer Dendright
  • Class Anti-inflammatories; Immunotherapies
  • Mechanism of Action Immunosuppressants; NF-kappa B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Autoimmune disorders

Highest Development Phases

  • No development reported Rheumatoid arthritis; Type 1 diabetes mellitus

Most Recent Events

  • 05 Nov 2021 Updated immunogenicity data from a phase I trial in Rheumatoid arthritis presented at the ACR Convergence 2021
  • 28 Dec 2020 No recent reports of development identified for phase-I development in Rheumatoid-arthritis(Adjunctive treatment) in Australia (SC, Injection)
  • 13 Nov 2019 Dendright completes a phase I trial in Rheumatoid arthritis (Adjunctive treatment) in Australia (SC) (ACTRN12617001482358)
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