Alidornase alfa

Drug Profile

Alidornase alfa

Alternative Names: AIR DNAse™; PRX 110

Latest Information Update: 08 Jun 2017

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At a glance

  • Originator Protalix BioTherapeutics
  • Class Antibacterials; Antifibrotics; Pentanoic acids; Recombinant proteins
  • Mechanism of Action Deoxyribonuclease 1 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis

Most Recent Events

  • 23 May 2017 Protalix Biotherapeutics completes a phase IIa trial in Cystic fibrosis (In adolescents, In adults, Treatment -experienced) in Israel (Inhalation) (NCT02722122)
  • 12 Apr 2017 Updated efficacy, antimicrobial and pharmacokinetics data from a phase II trial in Cystic fibrosis released by Protalix BioTherapeutics
  • 08 Feb 2017 Chemical structure information added
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