Drug Profile


Alternative Names: hpNSC; Human parthenogenetic neural stem cells - International Stem Cell Corporation; ISC-hpNSC

Latest Information Update: 20 Nov 2017

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At a glance

  • Originator Duke University; International Stem Cell Corporation
  • Developer International Stem Cell Corporation; Tulane University
  • Class Antiparkinsonians; Cell therapies; Stem cell therapies
  • Mechanism of Action Dopaminergic cell replacements; Nervous system modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Parkinson's disease
  • Preclinical Brain injuries; Stroke

Most Recent Events

  • 13 Nov 2017 Efficacy and safety data from a phase I trial in Parkinson's disease released by International Stem Cell Corporation
  • 31 Oct 2017 International Stem Cell Corporation receives patent allowance for methods for generating HLA homozygous parthenogenetic human stem cell lines in Australia
  • 20 Sep 2017 International Stem Cell Corporation announces intention to submit Clinical Trial Notification to Therapeutic Goods Administration in Australia for Brain injuries
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