NUC 3373

Drug Profile

NUC 3373

Alternative Names: 5-Fluorouracil ProTide - NuCana; NUC-3373

Latest Information Update: 12 Oct 2017

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At a glance

  • Originator Cardiff University
  • Developer NuCana
  • Class Antineoplastics; Pyrimidine nucleotides
  • Mechanism of Action DNA methylation inhibitors; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Breast cancer; Colorectal cancer; Solid tumours

Most Recent Events

  • 08 Sep 2017 Interim pharmacokinetics data from a phase I trial in Solid tumours presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017) (ADNM)
  • 15 Dec 2016 Biomarkers information updated
  • 22 Jul 2016 Phase-I clinical trials in Breast cancer and Colorectal cancer (unspecified route) (NuCana pipeline, July 2016)
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