Research programme: gene therapies - Adverum Biotechnologies

Drug Profile

Research programme: gene therapies - Adverum Biotechnologies

Alternative Names: AAV.7m8-aflibercept; AAV.7m8-ranibizumab; ADVM-022; ADVM-032; ANN 001; ANN-003; ANN-004

Latest Information Update: 20 Oct 2016

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At a glance

  • Originator Weill Cornell Medical College
  • Developer Adverum Biotechnologies; Weill Cornell Medical College
  • Class Antiallergics; Eye disorder therapies; Gene therapies; Heart failure therapies; Hepatoprotectants
  • Mechanism of Action Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Hypersensitivity; Wet age-related macular degeneration
  • Research Cardiomyopathies

Most Recent Events

  • 08 Nov 2017 Adverum Biotechnologies plans to file an IND application of ADVM 022 with the US FDA in USA for Wet age-related macular degeneration in the second half of 2018
  • 14 Oct 2016 Adverum Biotechnologies plans toxicological studies in Wet age-related macular degeneration ,
  • 14 Oct 2016 Adverum Biotechnologies plans to initiate enrolment in a phase I/II trial for Alpha-1 antitrypsin deficiency (Intravenous) (Intrapleural) (NCT02168686)
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