JNJ 63709178

Drug Profile

JNJ 63709178

Alternative Names: CD123 x CD3 DuoBody; CD123-CD3 DuoBody protein; CNTO 9958; JNJ-63709178

Latest Information Update: 11 Apr 2017

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At a glance

  • Originator Genmab; Janssen Research & Development
  • Developer Janssen Research & Development
  • Class Bispecific antibodies
  • Mechanism of Action CD3 antigen modulators; Interleukin 3 receptor alpha subunit modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia

Most Recent Events

  • 05 Apr 2017 Phase-I clinical trials in Acute myeloid leukaemia (Second-line therapy or greater) in USA (IV) (NCT02715011)
  • 16 Dec 2016 Biomarkers information updated
  • 06 Dec 2016 Pharmacodynamic results from a preclinical study in Acute myeloid leukaemia reported at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2016)
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