PTI 428

Drug Profile

PTI 428

Alternative Names: PTI-428

Latest Information Update: 11 Apr 2017

Price : $50

At a glance

  • Originator Proteostasis Therapeutics
  • Class Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cystic fibrosis

Highest Development Phases

  • Phase I Cystic fibrosis

Most Recent Events

  • 30 Mar 2017 Medicines and Healthcare products Regulatory Agency (UK) and Health Canada approves IND application for PTI 428 in Cystic fibrosis
  • 11 Aug 2016 Preliminary pharmacokinetics data from a phase I trial in Healthy volunteers released by Proteostasis Therapeutics
  • 01 Jun 2016 Proteostasis Therapeutics initiates a phase I trial in Healthy volunteers in USA (PO) (NCT02846142)
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