TSR 042

Drug Profile

TSR 042

Alternative Names: ANB 011; Anti-PD-1 mAb; Anti-PD-1 monospecific antagonist antibody; TSR-042

Latest Information Update: 17 Oct 2017

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At a glance

  • Originator AnaptysBio
  • Developer TESARO
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action PDCD 1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Endometrial cancer; Solid tumours

Most Recent Events

  • 12 Oct 2017 Tesaro plans a phase Ib trial for Cancer, including Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater, Combination therapy) in USA (Parenteral) (NCT03307785)
  • 11 Sep 2017 Safety and efficacy data from a phase I trial in Solid tumours released by TESARO
  • 08 Sep 2017 Safety, efficacy and pharmacokinetics data from a phase I trial in Solid tumours presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017)
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