Drug Profile
Valemetostat - Daiichi Sankyo
Alternative Names: DS-3201; DS-3201b; EZHARMIA; Valemetostat tosilate; valemetostat tosylateLatest Information Update: 14 Feb 2024
Price :
$50
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At a glance
- Originator Daiichi Sankyo Inc
- Developer CALYM Carnot Institute; Daiichi Sankyo Inc; Lymphoma Academic Research Organisation; Lymphoma Study Association; University of Texas M. D. Anderson Cancer Center
- Class Amides; Amines; Antineoplastics; Benzodioxoles; Chlorinated hydrocarbons; Cyclohexanes; Pyridones; Small molecules
- Mechanism of Action Enhancer of zeste homolog 1 protein inhibitors; Enhancer of zeste homolog 2 protein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Adult T-cell leukaemia-lymphoma
- Phase II B-cell lymphoma; Peripheral T-cell lymphoma
- Phase I/II Small cell lung cancer
- No development reported Acute myeloid leukaemia; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Prostate cancer; Renal cell carcinoma; Urogenital cancer
Most Recent Events
- 06 Feb 2024 Daiichi Sankyo Company plans a phase I trial for Solid tumors (Late-stage-diseases, Metastatic-diseases, Combination therapy) (NCT06244485, DS3201-324)
- 30 Jan 2024 Daiichi Sankyo files sNDA for treatment of adult patients with relapsed or refractory Peripheral T-cell lymphoma in Japan
- 28 Jan 2024 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma(Second-line therapy or greater) in Japan (PO, Tablet)