Research programme: anti-cancer therapeutics - Halozyme

Drug Profile

Research programme: anti-cancer therapeutics - Halozyme

Alternative Names: HTI-1511; PEG-ADA2; PEG-ADA2-E182T; PEG-ADA2-K374D; PEG-ADA2-R222Q-S265N; PEGylated adenosine deaminase 2

Latest Information Update: 05 Jun 2017

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At a glance

  • Originator Halozyme Therapeutics
  • Class Auristatins; Drug conjugates; Enzymes
  • Mechanism of Action Adenosine deaminase inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cholangiocarcinoma; Chronic lymphocytic leukaemia; Colorectal cancer; Lung cancer; Pancreatic cancer

Most Recent Events

  • 05 Apr 2017 Preclinical trials in Chronic lymphocytic leukaemia in USA (unspecified route)
  • 05 Apr 2017 Pharmacokinetics data from a preclinical study in Chronic lymphocytic leukaemia presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
  • 10 May 2016 Pharmacodynamics and pharmacokinetic data from a preclinical study in Solid tumour models presented at the107th Annual Meeting of the American Association for Cancer Research (AACR-2016)
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