Research programme: HuMab 5B1 radioimmunotherapy - MabVax

Drug Profile

Research programme: HuMab 5B1 radioimmunotherapy - MabVax

Alternative Names: 177Lu- CHX-A″-DTPA-HuMAb-5B1; 177Lu-DTPA-HuMab-5B; 90Y- CHX-A″-DTPA-HuMAb-5B1; HuMab 5B1 radioimmunotherapy agent - MabVax; HuMab-5B1 conjugated Actinium225-radioimmunotherapy agent; MVT 1075; MVT 1916; radiolabeled HuMab 5B1 antibody - MabVax

Latest Information Update: 23 May 2017

Price : $50

At a glance

  • Originator MabVax Therapeutics
  • Developer MabVax Therapeutics; Memorial Sloan-Kettering Cancer Center
  • Class Antibodies; Immunotherapies; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action Immunomodulators; Ionising radiation emitters; Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Pancreatic cancer

Most Recent Events

  • 05 Apr 2017 MabVax Therapeutics plans a phase II trial for Pancreatic cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) and CA19-9 positive malignancies in USA (NCT03118349)
  • 01 Apr 2017 Pharmacodynamics data from preclinical studies in Pancreatic cancer presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
  • 23 Feb 2017 The US FDA approves IND application for MVT 1075 in Pancreatic cancer
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