MCLA 117

Drug Profile

MCLA 117

Alternative Names: MCLA-117

Latest Information Update: 11 May 2017

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At a glance

  • Originator Merus
  • Developer Institute Gustave-Roussy; LGC; Merus; Pharmaceutical Research Associates; VU University Medical Center
  • Class Antineoplastics; Bispecific antibodies
  • Mechanism of Action C-type lectin-like molecule-1 protein modulators; CD3 antigen modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia
  • Preclinical Myelodysplastic syndromes

Most Recent Events

  • 03 May 2017 Merus announces intention to submit IND application to US FDA for a phase I trial of MCLA 117
  • 13 May 2016 Preclinical trials in Myelodysplastic syndromes in Netherlands (Parenteral)
  • 04 May 2016 Phase-I/II clinical trials in Acute myeloid leukaemia (In the elderly, Newly diagnosed) in Netherlands (Parenteral)
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