Ruxolitinib deuterated

Drug Profile

Ruxolitinib deuterated

Alternative Names: CTP-543; deuterated ruxolitinib; Deuterium modified ruxolitinib - Concert Pharmaceuticals

Latest Information Update: 19 May 2017

Price : $50

At a glance

  • Originator Concert Pharmaceuticals
  • Class 2 ring heterocyclic compounds; Cyclopentanes; Nitriles; Organic deuterium compounds; Pyrazoles; Pyrimidines; Pyrroles; Skin disorder therapies; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Alopecia areata

Most Recent Events

  • 17 May 2017 US FDA places clinical hold on a phase IIa trial for Alopecia areata
  • 02 May 2017 Adverse events data from phase I trials in Alopecia areata (In volunteers) released by Concert Pharmaceuticals
  • 01 May 2017 Phase-II clinical trials in Alopecia areata in USA (PO) (NCT03137381; 9215672)
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