GLPG 2451

Drug Profile

GLPG 2451

Alternative Names: GLPG2451

Latest Information Update: 22 Sep 2017

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At a glance

  • Originator Cystic Fibrosis Foundation Therapeutics; Galapagos NV
  • Developer Galapagos NV
  • Class Antifibrotics; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cystic fibrosis

Most Recent Events

  • 25 Aug 2017 Galapagos completes a phase I trial in Healthy volunteers (Combination therapy) in Belgium (PO) (NCT03214614)
  • 20 Jun 2017 Galapagos plans a triple combination therapy comprising GLPG 2451, GLPG 2222 and GLPG 2737 for Cystic fibrosis in the fourth quarter of 2017
  • 27 Apr 2017 Galapagos NV completes a phase I trial in Healthy volunteers (Combination therapy) in Belgium (PO) (NCT02788721)
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