DMT 200

Drug Profile

DMT 200

Alternative Names: DMT 210; DMT 220; DMT200; SIG 990

Latest Information Update: 28 Feb 2017

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At a glance

  • Originator Signum Biosciences
  • Developer Dermata Therapeutics; Signum Biosciences
  • Class Anti-inflammatories; Skin disorder therapies; Small molecules; Terpenes
  • Mechanism of Action G protein-coupled receptor antagonists; GTP-binding protein modulators; Interleukin 4 inhibitors; Interleukin 6 inhibitors; Interleukin-17 inhibitors; Toll like receptor 2 antagonists; Toll-like receptor 4 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atopic dermatitis; Rosacea
  • Preclinical Acne vulgaris

Most Recent Events

  • 28 Feb 2017 Early research in Rosacea in USA (Ophthalmic) (Dermata Therapeutics pipeline, February 2017)
  • 28 Feb 2017 Preclinical trials in Acne vulgaris in USA (Topical) (Dermata Therapeutics pipeline, February 2017)
  • 01 Jan 2017 Phase-II clinical trials in Rosacea in USA (Topical) (NCT03003104)
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