Research programme: lysosomal storage disease therapeutics - ArmaGen Technologies

Drug Profile

Research programme: lysosomal storage disease therapeutics - ArmaGen Technologies

Alternative Names: AGT-183; AGT-184; HIRMAb-ASA fusion protein - ArmaGen Technologies; IgG-ASA fusion protein - ArmaGen Technologies; Recombinant N-sulphoglucosamine sulphohydrolase - ArmaGen Technologies; Recombinant sulfamidase - ArmaGen Technologies

Latest Information Update: 04 Jul 2016

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At a glance

  • Originator ArmaGen Technologies
  • Developer ArmaGen Technologies; Department of Veterans Affairs; Saint Louis University; University of California at Los Angeles; University of Texas Medical Branch
  • Class Arylsulfatases; Enzymes; Immunoglobulin fusion proteins; Monoclonal antibodies
  • Mechanism of Action Arylsulfatase replacements; Enzyme replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Metachromatic leukodystrophy; Mucopolysaccharidosis III

Most Recent Events

  • 04 Jul 2016 Preclinical development is ongoing for Mucopolysaccharidosis III and Metachromatic leukodystrophy in USA (ArmaGen Technologies pipeline, July 2016)
  • 25 Dec 2012 Preclinical trials in Metachromatic leukodystrophy in USA (IV) before December 2012
  • 29 Apr 2008 Preclinical trials in Mucopolysaccharidosis III in USA (IV) before April 2008
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