Drug Profile


Alternative Names: (+)-Alpha-Dihydrotetrabenazine; HTBZ

Latest Information Update: 30 Aug 2017

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At a glance

  • Originator Adeptio Pharmaceuticals
  • Developer Adeptio Pharmaceuticals; University of Michigan
  • Class Quinolizines; Small molecules
  • Mechanism of Action Dopamine receptor antagonists; Vesicular monoamine transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Neurological disorders

Most Recent Events

  • 27 Jun 2017 University of Michigan and Adeptio Pharmaceuticals completes a phase I trial in Neurological disorders (In volunteers) in USA (PO) (NCT02844179)
  • 15 Sep 2016 Chemical structure information added
  • 01 Jul 2016 Phase-I clinical trials in Neurological disorders (In volunteers) in USA (PO) (NCT02844179)
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