Drug Profile


Alternative Names: BNZ-1; BNZ132-1; BNZ132-1-40

Latest Information Update: 19 Sep 2017

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At a glance

  • Originator Bioniz
  • Developer Bioniz; National Institutes of Health (USA)
  • Class Anti-inflammatories; Peptides
  • Mechanism of Action Immunomodulators; Interleukin 15 receptor antagonists; Interleukin 2 receptor antagonists; Interleukin 9 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cutaneous T cell lymphoma; T-cell leukaemia
  • Phase I Alopecia areata
  • Preclinical Tropical spastic paraparesis

Most Recent Events

  • 13 Sep 2017 Phase-I/II clinical trials in Cutaneous T-cell lymphoma (Second-line therapy or greater) (IV) (NCT03239392)
  • 13 Sep 2017 Phase-I/II clinical trials in T-cell leukaemia (Second-line therapy or greater) (IV) (NCT03239392)
  • 11 Sep 2017 Bioniz Therapeutics initiates enrolment in a phase I trial in healthy volunteers in USA (NCT03239379)
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