Drug Profile


Alternative Names: anti-HPV016 E7 TCR; E7 TCR gene therapy; E7-TCR; HPV-16 E7 TCR

Latest Information Update: 04 Oct 2017

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At a glance

  • Originator National Cancer Institute (USA)
  • Developer Kite Pharma; National Cancer Institute (USA)
  • Class Gene therapies; T lymphocyte cell therapies
  • Mechanism of Action Gene transference; Human papillomavirus E7 protein modulators; T-cell receptor antigen modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Cervical cancer; Head and neck cancer; Urogenital cancer

Most Recent Events

  • 03 Oct 2017 Kite Pharma has been acquired by Gilead Sciences
  • 01 Jul 2016 Phase-I clinical trials in Cervical cancer in USA (IV) (NCT02858310)
  • 01 Jul 2016 Phase-I clinical trials in Urogenital cancer in USA (IV) (NCT02858310)
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