XmAb 14045

Drug Profile

XmAb 14045

Alternative Names: XmAb®14045

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Xencor
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action CD3 antigen modulators; Interleukin 3 receptor alpha subunit modulators; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Haematological malignancies

Most Recent Events

  • 12 Sep 2016 Phase-I clinical trials in Haematological malignancies in USA (IV)
  • 28 Jun 2016 Xencor and Novartis agree to co-promote and co-develop XmAb® 14045 for Acute myeloid leukaemia
  • 31 Mar 2016 Xencor plans a phase I trial for Haematological malignancies in USA (NCT02730312)
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