Anti-PDL1 chimeric switch receptor modified T-cell therapy - Marino Biotechnology

Drug Profile

Anti-PDL1 chimeric switch receptor modified T-cell therapy - Marino Biotechnology

Alternative Names: Anti-PD-L1 CSR T cells - Marino Biotechnology; Anti-PDL1 chimeric antigen receptor T-cell therapy - Marino Biotechnology; Autologous anti- PD-L1 CSR T cells - Marino Biotechnology

Latest Information Update: 21 Oct 2016

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At a glance

  • Originator Marino Biotechnology
  • Class Antineoplastics; CAR-T cell therapies; T lymphocyte cell therapies
  • Mechanism of Action CD274 antigen inhibitors; Cytotoxic T lymphocyte stimulants; Gene transference; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Glioblastoma; Solid tumours

Most Recent Events

  • 01 Aug 2016 Phase-I clinical trials in Solid tumours (Metastatic disease, Recurrent) in China (IV) (NCT02930967)
  • 01 Jul 2016 Phase-I clinical trials in Glioblastoma (Recurrent, Second-line therapy or greater) in China (IV) (NCT02930967)
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