Lamivudine/tenofovir disoproxil fumarate

Drug Profile

Lamivudine/tenofovir disoproxil fumarate

Latest Information Update: 12 Dec 2016

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At a glance

  • Originator Merck Sharp & Dohme
  • Developer INSERM; Merck Sharp & Dohme; UNITAID
  • Class Antiretrovirals; Deoxyribonucleosides; Dideoxynucleosides; Phosphonic acids; Purines; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action Nucleoside reverse transcriptase inhibitors; Nucleotide reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase III HIV-1 infections

Most Recent Events

  • 12 Dec 2016 Chemical structure information added
  • 28 Nov 2016 Merck Sharp & Dohme plans a phase I trial for HIV-1 infections (In volunteers) in Canada (PO) (EudraCT2016-004392-41)
  • 01 Jul 2016 Phase-III clinical trials in HIV-1 infections in Cameroon (PO) (NCT02777229)
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