PEN 221

Drug Profile

PEN 221

Alternative Names: BTP-227; PEN221

Latest Information Update: 14 Mar 2017

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At a glance

  • Originator Tarveda Therapeutics
  • Class Antineoplastics; Drug conjugates
  • Mechanism of Action DNA cross linking agents; DNA synthesis inhibitors; Somatostatin receptor 2 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Neuroendocrine tumours; Small cell lung cancer

Most Recent Events

  • 09 Dec 2016 PEN 221 is available for licensing as of 09 Dec 2016.
  • 01 Nov 2016 Phase-I/II clinical trials in Neuroendocrine tumours (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT02936323)
  • 01 Nov 2016 Phase-I/II clinical trials in Small cell lung cancer (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT02936323)
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