SPR 741

Drug Profile

SPR 741

Alternative Names: SPR 741

Latest Information Update: 17 Oct 2017

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At a glance

  • Originator Northern Antibiotics
  • Developer Evotec AG; Spero Therapeutics
  • Class Antibacterials; Peptides; Polymixins
  • Mechanism of Action Bacterial outer membrane protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Gram-negative infections

Most Recent Events

  • 03 Oct 2017 Spero Therapeutics plans a phase II combination trial of SPR 741
  • 01 Sep 2017 Spero Therapeutics completes a phase I trial in Gram-negative infections (In volunteers) in Australia (IV) (NCT03022175)
  • 02 May 2017 Spero Therapeutics plans a clinical trial for Gram-negative infections (Combination therapy with SPR 720) in 2017
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