VX 659

Drug Profile

VX 659

Alternative Names: VX659

Latest Information Update: 13 Sep 2017

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At a glance

  • Originator Vertex Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis

Most Recent Events

  • 08 Aug 2017 Phase-II clinical trials in Cystic fibrosis (Combination therapy) in United Kingdom, Ireland, USA (PO) (NCT03224351) (EudraCT2016-003585-11)
  • 01 Aug 2017 Vertex Pharmaceuticals completes a phase I trial for Cystic fibrosis (Monotherapy and Combination therapy) in United Kingdom (NCT03029455)
  • 18 Jul 2017 Vertex Pharmaceuticals plans a phase II trial for Cystic fibrosis (Combination therapy) in early August 2017 (PO) (NCT03224351) (EudraCT2016-003585-11)
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