Drug Profile


Alternative Names: 11 1F4; CAEL 101; Ch mAb 11-1F4

Latest Information Update: 11 Aug 2017

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At a glance

  • Originator Columbia University
  • Developer Caelum Biosciences; Columbia University; National Cancer Institute (USA)
  • Class Monoclonal antibodies
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyloidosis; Amyloid light-chain amyloidosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Amyloid light-chain amyloidosis

Most Recent Events

  • 09 Aug 2017 Columbia University files a second provisional patent application for CAEL 101 in the US
  • 17 Jul 2017 Columbia University files a provisional patent application for CAEL 101 in the US
  • 01 Jun 2017 Caelum Biosciences and Patheon enter into a manufacturing agreement for Amyloid light chain amyloidosis
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