Chimeric antigen receptor T-cell therapy - Juno Therapeutics

Drug Profile

Chimeric antigen receptor T-cell therapy - Juno Therapeutics

Alternative Names: Armored CAR modified T Cells; CD19-directed 4-1BBL armored CAR - Juno Therapeutics; EGFRt/19-28z/4-1BBL CAR T cells

Latest Information Update: 04 Apr 2017

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At a glance

  • Originator Juno Therapeutics
  • Developer Juno Therapeutics; Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics; CAR-T cell therapies
  • Mechanism of Action Cell replacements; Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia

Most Recent Events

  • 15 Mar 2017 Phase-I clinical trials in Chronic lymphocytic leukaemia (Refractory metastatic disease, Recurrent) in USA (Parenteral) (NCT03085173)
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