LN 145

Drug Profile

LN 145

Alternative Names: Autologous tumour infiltrating lymphocytes - Iovance Biotherapeutics; LN-145

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator National Cancer Institute (USA); National Institutes of Health (USA)
  • Developer Iovance Biotherapeutics
  • Class Antineoplastics; T lymphocyte cell therapies
  • Mechanism of Action Immunomodulators; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Cervical cancer; Head and neck cancer

Most Recent Events

  • 13 Sep 2017 Iovance Biotherapeutics receives approval for clinical trial application for initiation of a phase II trial for Cervical cancer (Recurrent, Metastatic disease) in Netherlands
  • 31 Aug 2017 Iovance Biotherapeutics files clinical trial applications in Europe for Cervical cancer and Malignant melanoma (Metastatic diseases)
  • 27 Jun 2017 Lion Biotechnologies is now called Iovance Biotherapeutics
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